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Infectious Diseases
These videos cover advancements in a variety of infectious diseases, most notably SARS-CoV-2.
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mRNA-1273 or mRNA-Omicron boost in vaccinated macaques elicits similar B cell expansion, neutralizing responses, and protection from Omicron
Dr Matthew Gagne from Dr Daniel Douek lab speaks of his latest findings on the benefits of a vaccine boost using the original vs the Omicron strain.
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Germinal centre-driven maturation of B cell response to mRNA vaccination
Dr Jackson Turner from Ali Ellebedy lab at Washington University School of Medicine in St. Louis describes the evolution of B-cells following vaccination against Covid-19.
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High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cells
In this video, Jennifer Chen from the Eisenbarth Lab in collaboration with Wilen lab at Yale University tells us their latest findings on different types of T- follicular helper cells and role in the context of infectious diseases.
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Let's Prime and Boost!
Professor Akiko Iwasaki from Yale School of Medicine describes an efficient strategy called Prime and Boost to increase immune responses against Covid-19.
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https://www.biorxiv.org/content/10.1101/2022.01.24.477597v1
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https://www.biorxiv.org/content/10.1101/2022.01.24.477597v1
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The Use of Boosters in Response to Latest Covid-19 Variants
Professor Akkiko Iwasaki from Yale University details her latest studies on the antibody response induction against latest Sars-CoV-II variants in the context of vaccination and the use of boosters.
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LINK - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938264/
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LINK - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8938264/
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Endotracheal Application of Ultraviolet A Light in Critically Ill Patients with Severe Acute Respiratory Syndrome Coronavirus 2: A First-in-Human Study
Dr Ali Rezaie from UCLA describes his latest discovery on Endotracheal Application of Ultraviolet A Light as a potential treatment against Covid-19.
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LINK - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234768/
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LINK - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8234768/
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Is a vaccine mandatory amongst COVID-19 infection?
Dr Nabin Shrestha from Cleveland Clinic reveals his study on the importance of vaccination in previously infected vs non-infected individuals with SARS-CoV-II.
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LINK - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807217/
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LINK - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8807217/
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Evolution of Sars-CoV-II
Dr. Nathaniel landau from NYU describes two of his latest findings regarding emerging mutants and their consequences.
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312895/
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8312895/
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Oral Vaccine Against Covid-19
Dr. David Klatzmann, Professor of Immunology at Sorbonne Université, describes his study on developing an oral vaccine providing mucosal immunity.
Oral Vaccine Against Covid-19
LINK - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913903/
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Oral Vaccine Against Covid-19
LINK - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913903/
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How Air Filtration Can Decrease Airborne Viruses
Dr. Vilas Navapurkar from Cambridge University Hospital NHS Foundation Trust describes his latest findings on the benefits of air filtration in clearing airborne pathogens including Sars-CoV-II.
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LINK - https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab933/6414657?guestAccessKey=248e14cc-d920-4782-99b7-634e47cdaa0e&login=true
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LINK - https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciab933/6414657?guestAccessKey=248e14cc-d920-4782-99b7-634e47cdaa0e&login=true
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Emotional being, sleep, and COVID-19
In his latest research, Dr. Anthony Cunningham from Harvard Medical School details people's state of mind on the days following the COVID-19 pandemic.
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LINK - https://www.nature.com/articles/s41597-021-00886-y
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LINK - https://www.nature.com/articles/s41597-021-00886-y
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SARS-CoV-2 interactions with host genes
Dr Craig Wilen from Yale University describe a study identifying uncharacterized host genes important in SARS-CoV-2 infection.
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LINK - https://www.cell.com/cell/fulltext/S0092-8674(20)31392-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867420313921%3Fshowall%3Dtrue
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LINK - https://www.cell.com/cell/fulltext/S0092-8674(20)31392-1?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867420313921%3Fshowall%3Dtrue
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A way to study entry in biosafety level 2 lab
Dr Robert Stahelin and graduate student Caroline Plescia from Purdue University describe their latest innovative models on how to study SARS-Cov-2 entry and budding on a BSL-2 environment.
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LINK - https://pubmed.ncbi.nlm.nih.gov/33214224/
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LINK - https://pubmed.ncbi.nlm.nih.gov/33214224/
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SARS-Cov-2 Cell Entry in a BSL2 lab
Dr Rohit Jangra, Dr M. Eugenia Dieterle and Dr Denise Haslwanter from Albert Einstein College of Medicine describe their recent findings on the generation of recombinant virus that include SARS-CoV-2 spike protein to study viral entry and immune response in a BSL-2 facility.
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LINK - https://pubmed.ncbi.nlm.nih.gov/32738193/
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LINK - https://pubmed.ncbi.nlm.nih.gov/32738193/
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COVID-19 in Iceland
Dr Stefansson from deCODE genetics explains his latest findings related to the induced immunity in patients from Iceland following SARS-COV-2 infection.
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LINK - https://www.nejm.org/doi/full/10.1056/NEJMoa2026116
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LINK - https://www.nejm.org/doi/full/10.1056/NEJMoa2026116
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Immune response of vaccines in mice models
Dr Dorottya Laczkó of UPenn summarizes her studies on vaccines equivalent of the one from Pfizer and Moderna in mouse models.
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LINK - https://www.sciencedirect.com/science/article/pii/S1074761320303265?casa_token=nPBey2d8u4wAAAAA:l__-Ilm6sOLnPs2yBp15EHbcJvJmnf58XU-4p_VuWtTdgnY2xy_Rlh7BghONZz3nkgflkHG94g
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LINK - https://www.sciencedirect.com/science/article/pii/S1074761320303265?casa_token=nPBey2d8u4wAAAAA:l__-Ilm6sOLnPs2yBp15EHbcJvJmnf58XU-4p_VuWtTdgnY2xy_Rlh7BghONZz3nkgflkHG94g
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COVID-19 and Immune Profiling
Dr. Tracy Hussell from the Lydia Becker Institute of Immunology and Inflammation describes her research on profiling the immune response upon SARS-COV-2 infection.
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LINK - https://immunology.sciencemag.org/content/5/51/eabd6197
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LINK - https://immunology.sciencemag.org/content/5/51/eabd6197
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